The Treatment-Resistant File
Roughly a third of people with major depression do not respond to the first two medications they try. That does not mean they are out of options. A plain-language map of what comes after the standard prescription.
[ 04 ] PTSD desk
Post-traumatic stress is treatable, and the tools have widened
Trauma-focused therapy remains first-line, but for veterans and others in the region, newer options are reshaping the conversation.
[ 05 ] Local resources
How to actually get help near you, step by step
From a primary-care conversation to a specialty consult, a concrete path for St. Charles County and greater St. Louis.
[ 06 ] Treatment desk
What to expect at a monitored esketamine appointment
Two hours in a certified setting, a treatment schedule, and a plan for the drive home. The logistics that patients ask about most.
[ 07 ] Depression desk
The vocabulary of “treatment-resistant” depression, decoded
Augmentation, switching, combination. The words a clinician uses when the first plan stalls, and what each one means.
[ 08 ] Treatment desk
Is TMS right for you? The questions worth asking first
A short, honest checklist to bring to a consultation, plus the situations where TMS is usually not the starting point.
[ 09 ] Cost & coverage
Prior authorization, translated into plain English
Why insurers require it, how long it takes, and what to do when a first request comes back denied.
Health wire · last 30 days